Coffee & chat: Non-medical switching
Dive into the detail in this Bayer organised series of short videos as GP Dr Yassir Javaid and Consultant Cardiologist Dr Raj Mattu explore the considerations around switching Direct-Acting Oral Anticoagulants (DOACs) in patients with NVAF and the implications of non-clinical DOAC-to-DOAC switching for both the patient and the NHS. A summary of the discussion is also available to download in PDF format.
Download this guide to explore the impact of non-medical switching on high-risk patients with NVAF.
View Prescribing Information and Adverse Event Reporting.
Dr Javaid and Dr Mattu use patient case examples to further explore the considerations when switching from DOAC to DOAC.
Download this article which summarises Dr Javaid and Dr Mattu's discussion on non-medical switching between DOACs for stroke prevention in non-valvular atrial fibriallation.
A practical guide on the key clinical differences between DOACs
This guide highlights some of the clinical considerations in relation to DOACs use that clinicians and payors may wish to consider before making large-scale switch or formulary status decisions.
A practical guide to support what dose of DOAC to prescribe according to the renal function.
Renal function, including extremes of CrCl, is one of many important factors when individualising anticoagulation therapy for patients with NVAF.
Up to 22% of the NVAF population may haveCrCl > 95mL/min[4][5][6]
Footnotes
NVAF, non-valvular atrial fibrillation; DOAC, direct oral anticoagulant; PCN, primary care network; CrCl, creatinine clearance
RP-XAR-GB-5142 | February 2024
- Referencesexpand_less
- 1NHS 2022. Operational note: Commissioning recommendations for national procurement for DOACs. Available at: https://www.england.nhs.uk/wp-content/uploads/2022/01/B1279-national-procurement-for-DOACs-commissioning-recommendations-v1.pdf (Last Accessed February 2024)
- 2NICE Clinical Guideline (NG196). Available at: https://www.nice.org.uk/guidance/ng196 (Last Accessed February 2024)
- 3BMA 2018. Prescribing in General Practice. Available at: https://www.bma.org.uk/media/1563/bma-prescribing-in-general-practice-april-2018.pdf (Last Accessed February 2024)
- 4UKKA CKD classification. Available at: https://ukkidney.org/health-professionals/information-resources/uk-eckd-guide/ckd-stages (Last Accessed February 2024)
- 5Specialist Pharmacy Service: DOACs (Direct Oral Anticoagulants) monitoring. Available at: https://www.sps.nhs.uk/monitorings/doacs-direct-oral-anticoagulants-monitoring/ (Last Accessed February 2024)
- 6Bohula EA, et al. Circulation 2016;134:24-36