Conversations at ESMO 2025
Doublet and triplet therapy in mHSPC – Who is the right patient?

During ESMO 2025, we had the honour of engaging with leading clinical experts in prostate cancer care to delve into a pivotal question regarding metastatic hormone-sensitive prostate cancer (mHSPC): With NUBEQA (darolutamide) available both as a doublet and triplet therapy alongside docetaxel, in which patient populations should we consider intensifying treatment?
Featuring:
In this insightful video, Professor Birtle addresses the pressing question: Is doublet therapy the way to go, or should we opt for triplet therapy in mHSPC? Highlights include:
- Factors Influencing Treatment Intensification: Discover the patient characteristics that guide decisions on intensifying therapy.
- Impact of NUBEQA (darolutamide): Explore how the availability of NUBEQA as both a doublet and triplet therapy is reshaping treatment approaches.
Real-World Applications
In a compelling discussion, Professor Suneil Jain and Dr. Balaji Venugopal share invaluable case studies showcasing their experiences with NUBEQA as a doublet treatment in mHSPC. They discuss how the flexibility of NUBEQA (darolutamide) as a doublet and triplet therapy in mHSPC, has addressed unmet needs in their clinical practice.
PP-NUB-GB-2751 | March 2026


