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Oncology Podcasts

Conversations at ESMO 2025

Doublet and triplet therapy in mHSPC – Who is the right patient?

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During ESMO 2025, we had the honour of engaging with leading clinical experts in prostate cancer care to delve into a pivotal question regarding metastatic hormone-sensitive prostate cancer (mHSPC): 

With NUBEQA (darolutamide) available both as a doublet and triplet therapy alongside docetaxel, in which patient populations should we consider intensifying treatment?

Featuring:

In this insightful video, Professor Birtle addresses the pressing question: Is doublet therapy the way to go, or should we opt for triplet therapy in mHSPC? Highlights include:

  • Factors Influencing Treatment Intensification:
     Discover the patient characteristics that guide decisions on intensifying therapy.
  • Impact of NUBEQA (darolutamide):
     Explore how the availability of NUBEQA as both a doublet and triplet therapy is reshaping treatment approaches.

Real-World Applications

In a compelling discussion, Professor Suneil Jain and Dr. Balaji Venugopal share invaluable case studies showcasing their experiences with NUBEQA as a doublet treatment in mHSPC. They discuss how the flexibility of NUBEQA (darolutamide) as a doublet and triplet therapy in mHSPC, has addressed unmet needs in their clinical practice.

 

PP-NUB-GB-2751 | November 2025