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Oncology Podcasts

Conversations at ESMO 2025

Considering comorbidities in your mHSPC patients

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At ESMO 2025, we had the privilege of sitting down with Dr. Mark Prentice to discuss a critical clinical question in the realm of metastatic hormone-sensitive prostate cancer (mHSPC): 

Which androgen receptor pathway inhibitor (ARPI) can effectively meet our treatment goals without compromising the patient’s quality of life?

Featuring:

    Dr Mark Prentice is a consultant in Clinical Oncology at the Royal Free Hospital NHS Foundation Trust. He is the principal investigator for multiple clinical trials and has written international guidelines on prostate cancer management. Mark’s main research interests are in novel radiotherapy techniques, radio-ligand therapy, the hormonal manipulation of prostate cancer and the management of older people with cancer.

In this engaging video, Dr Prentice tackles essential clinical topics, including 

  • NUBEQA (darolutamide) as a doublet treatment: 
    how does the availability of another ARPI option in this space address unmet needs?
  • Prioritising quality of life: 
    keeping quality of life at the heart of treatment decision making
  • Balancing comorbidities: 
    navigating cardiovascular conditions, patient frailty and potential drug-to-drug interactions in mHSPC patients

NUBEQA® (darolutamide) Prescribing Information

ESMO 2025
NUBEQA® (darolutamide)
PP-NUB-GB-2700, October 2025
Conversations at ESMO 2025
Doublet and triplet therapy in mHSPC – Who is the right patient?
PP-NUB-GB-2751, November 2025
NUBEQA® (darolutamide) Resources
PP-NUB-GB-2048, February 2025

PP-NUB-GB-2752 | November 2025