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Oncology Podcasts

Conversations at ESMO 2025

Considering comorbidities in your mHSPC patients

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At ESMO 2025, we had the privilege of sitting down with Dr. Mark Prentice to discuss a critical clinical question in the realm of metastatic hormone-sensitive prostate cancer (mHSPC): 

Which androgen receptor pathway inhibitor (ARPI) can effectively meet our treatment goals without compromising the patient’s quality of life?

Featuring:

In this engaging video, Dr Prentice tackles essential clinical topics, including 

  • NUBEQA (darolutamide) as a doublet treatment: 
    how does the availability of another ARPI option in this space address unmet needs?
  • Prioritising quality of life: 
    keeping quality of life at the heart of treatment decision making
  • Balancing comorbidities: 
    navigating cardiovascular conditions, patient frailty and potential drug-to-drug interactions in mHSPC patients

PP-NUB-GB-2752 | November 2025